Phytoquest Compound Libraries

Phytoquest has developed four different libraries with the following characteristics:

Library Name Description Details
Phytopure Library Pure mainly non-polar compounds ~1,000 compounds that are not commercially available and of which approximately 700 are novel
Fraction Library Less pure non-polar compounds ~3,000 fractions
Diversity Library Commercially-available compounds ~100 compounds supplied on micro-titre plates for screening purposes
Iminosugar Library Mainly unavailable elsewhere ~100 compounds and ongoing program of characterization

Careful selectivity inherent in the Phytoquest methods ensures that Phytopure and Fraction libraries display DIVERSITY, NOVELTY and FUNCTION as described below:


  • Isolated from over 750 plant genera including annuals, perennials, shrubs & trees
  • Plants are mainly temperate and obtained from many different habitats including cultivated sites and wild locations and many grown by PhytoQuest
  • Several extraction routes utilized resulting in compounds of widely ranging polarity
  • A broad range of chemical classes represented
  • Ubiquitous plant compounds avoided at compound isolation stage


  • Abundance of novel compounds is a prerequisite for plant selection
  • For each selected plant only those fractions containing novel compounds progress
  • Isolation of duplicate and commercially available compounds avoided by 2-stage spectral matching
  • PhytoQuest superior techniques and experienced chemists enable the isolation of more unusual compounds
  • Structural database matching ensures no duplication within library
  • All compounds checked against commercial databases to confirm non-availability from other sources
  • Selectivity results in two thirds of Phytopure being novel (as determined by Chapman & Hall Dictionary of Natural Products) with the remaining third not commercially available


  • PhytoQuest ensures that compounds with molecular weights outside the pharmaceutical-relevant range are rejected
  • A high degree of functionality (displayed by absorbance spectra) is used as a criteria for selecting compounds for isolation
  • Chromatographic methods used ensure that logP’s of compounds fall within Lipinski parameters
  • Certain chemical groups (eg pigments and fats) are avoided during isolation
Phytoquest management follow a best practice based approach to the management of the Libraries, focused on ensuring provenance and reproducibility:


  • Identification of all plants material is confirmed by in-house taxonomic experts
  • Batches of plant material are logged and tracked


  • PhytoQuest has grown many the source plants (glasshouse and in field plots) to reduce environment-related variability of the material
  • Drying and storage methods are also carefully followed
  • Inventory of many plants are kept dried and frozen for resupply of compounds
Phytoquest also focuses on delivering a library product that is easy to use in a range of analytical settings:

Ease of use

  • Compounds and fractions are typically supplied at 100µg dried in 96-well micro-titer plates
  • Types of plate and plate layout can be defined by the customer
Download the summary of Phytoquest
Compound Libraries

NMR Services for Industry and Academia

1H, 13C, DEPT, 2D, quantitative analyses, structural elucidation.

PhytoQuest Limited offers fast and high quality NMR analysis and interpretation using a Bruker Avance 500 MHz instrument:
  • 1D techniques such as 1H proton and 13C DEPT
  • 2D correlation (COSY, HMQC, HMBC, NOESY) NMR
  • Stereochemical configuration
  • Molecular structure determination
  • Impurity analysis and identification in samples
  • Chemicals, solvents, pharmaceuticals, natural products
  • Batch variation/Quality control
  • Metabolomics
  • Stability studies
  • Data Interpreted
  • ACD Prediction Software
  • Reports and spectra provided in electronic format
  • Reasonable rates
Download the summary of Phytoquest
NMR Services

For any further information about our services, or in order to receive an estimate, fell free to contact us at following
email address or use the contact form.